Dinutuximab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A chimeric mouse/human monoclonal antibody with potential antineoplastic activity. Dinutuximab binds to the ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. GD2 is overexpressed in malignant melanoma, neuroblastoma, osteosarcoma, and small cell carcinoma of the lung.

**Synonyms:** - Ch 14.18UTC - Ch14.18 - Ch14.18 - DINUTUXIMAB - Dinutuximab Beta - MOAB Ch14.18 - Qarziba - Unituxin - monoclonal antibody Ch14.18