tGLI1 Allele

**Semantic type:** Gene or Genome

**Definition:** Human tGLI1 allele is located in the vicinity of 12q13.3 and is approximately 12 kb in length. This allele, which encodes truncated glioma-associated oncogene homolog 1 protein, is involved in the modulation of transcription by RNA polymerase II. Expression of this allele is associated with glioblastoma multiforme (GBM).

**Synonyms:** - TGLI1 - Truncated GLI Family Zinc Finger 1 Allele - Truncated GLI1 Gene - Truncated Glioma-Associated Oncogene Homolog 1 Gene - tGLI