Castration-Resistant Prostate Carcinoma Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents

**Semantic type:** Neoplastic Process

**Definition:** Castration-resistant prostate carcinoma that is refractory to second-generation androgen receptor axis-targeted agents, namely abiraterone and enzalutamide.

**Synonyms:** - Castration-Resistant Prostate Carcinoma Refractory to Second-Generation ARAT Agents