Autologous Cytotoxic T-lymphocytes Exposed to Dendritic Cells loaded with 6B11 Anti-idiotype Minibody

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of autologous cytotoxic T-lymphocytes (CTLs) that are exposed, ex vivo, to autologous dendritic cells (DCs) loaded with the anti-idiotype minibody 6B11, which mimics the epithelial ovarian tumor-associated antigen (TAA), OC166-9, with potential immunostimulatory and antineoplastic activities. Upon administration, the CTLs exposed to DCs loaded with 6B11 anti-idiotype minibody target and kill autologous ovarian cells expressing the TAA.

**Synonyms:** - 6B11 Anti-idiotype Minibody-pulsed DCs Induced Autologous CTLs - Autologous CTLs Exposed to 6B11-OCIK - Autologous CTLs Exposed to 6B11mini-ovarian-cytokine-induced-killer Cells - Autologous CTLs Induced with 6B11 Anti-idiotype Minibody-pulsed DCs - Autologous Cytotoxic T-cells Induced by Autologous Dendritic Cells Loaded with 6B11 Anti-idiotype Minibody