CDK12 Loss of Function Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the CDK12 gene that either inhibits expression or results in the translation of an inactive cyclin-dependent kinase 12 protein.

**Synonyms:** - CDC2 Related Protein Kinase 7 Gene Loss of Function Mutation - CDK12 Inactivating Gene Mutation - CDK12 Inactivating Mutation - CDK12 Loss of Function Gene Mutation - CRK7 Loss of Function Mutation - CRKR Loss of Function Mutation - CRKRS Loss of Function Mutation - Cdc2-Related Kinase, Arginine/Serine-Rich Gene Loss of Function Mutation - Cyclin Dependent Kinase 12 Gene Loss of Function Mutation - Cyclin-Dependent Kinase 12 Gene Loss of Function Mutation - Inactivating CDK12 Gene Mutation - Inactivating CDK12 Mutation