PEG4000/Simethicone/Sodium Sulphate/Sodium Bicarbonate/Electrolytes Oral Solution

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A powder for oral solution containing polyethylene glycol (PEG) 4000 (Macrogol 4000), simethicone, sodium sulphate, sodium bicarbonate, and electrolytes, with laxative and bowel cleansing activities. Upon oral administration, macrogol 4000-based oral osmotic laxative promotes the retention of water in the bowel, thereby increasing the water content of stool, which results in increased gastrointestinal (GI) motility, accelerated stool transit time and evacuation of colonic contents.

**Synonyms:** - Macrogol 4000-based Oral Osmotic Laxative - PEG4000/Simethicone/Sodium Sulphate/Sodium Bicarbonate/Electrolytes - Powder-for-oral-solution containing PEG4000/Simethicone/Sodium Sulphate/Sodium Bicarbonate/Electrolyte - SELG-ESSE