IMWG Flow MRD-negative

**Semantic type:** Intellectual Product

**Definition:** Absence of phenotypically aberrant clonal plasma cells by next-generation flow cytometry on bone marrow aspirates using the EuroFlow standard operation procedure for minimal residual disease detection in multiple myeloma (or validated equivalent method) with a minimum sensitivity of 1 in 10^5 nucleated cells or higher.

**Synonyms:** - Flow MRD-negative - Flow Minimal Residual Disease-negative