Activating Non-V600 BRAF Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the BRAF gene that occurs outside of codon 600 and results in activation of both serine/threonine-protein kinase B-raf and its downstream signaling pathways.

**Synonyms:** - Activating Non-Codon 600 BRAF Gene Mutation - Activating Non-Codon 600 BRAF Mutation - BRAF Class II Alteration - BRAF Class II Mutation - Class 2 BRAF Mutation - Class II BRAF Alteration - Class II BRAF Mutation - Non-Codon 600 Activating BRAF Gene Mutation - Non-Codon 600 Activating BRAF Mutation - Non-Codon 600 Activating BRAF1 Mutation - Non-Codon 600 B-RAF Activating Mutation - Non-Codon 600 B-RAF1 Activating Mutation - Non-Codon 600 BRAF Activating Mutation - Non-V600 Activating BRAF Mutation