Dose-adjusted R-EPOCH Plus High-dose Methotrexate Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of rituximab, etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin (R-EPOCH) in a dose-adjusted (DA) version with high dose methotrexate that can be used for the treatment of non-Hodgkin lymphoma (NHL).

**Synonyms:** - DA-EPOCH-R/HD-M - DA-EPOCH-R/High-dose Methotrexate - DA-EPOCH-R/High-dose Methotrexate Regimen - DA-R-EPOCH Plus High-dose Methotrexate - DA-R-EPOCH Plus High-dose Methotrexate Regimen - DA-R-EPOCH/HD-M - Dose-adjusted Rituximab/Etoposide/Prednisone/Vincristine/Cyclophosphamide/Doxorubicin with High-dose Methotrexate