Camizestrant

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, camizestrant binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.

**Synonyms:** - AZ-14066724 - AZD 9833 - AZD-9833 - AZD9833 - CAMIZESTRANT - N-(1-(3-Fluoropropyl)-3-azetidinyl)-6-((6S,8R)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3H-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamine - SERD AZD9833 - Selective Estrogen Receptor Degrader AZD9833