PLCB4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PLCB4 wild-type allele is located within 20p12.3-p12.2 and is approximately 412 kb in length. This allele, which encodes 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 protein, plays a role in diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) synthesis. Mutation of the gene is associated with auriculocondylar syndrome 2.

**Synonyms:** - ARCND2 - DJ1119D9.2 - PI-PLC - Phopholipase C, Beta-4 Gene - Phospholipase C Beta 4 wt Allele - Phospholipase C, Beta 4 Gene