C161561Level 3
Rodent Progressive Cardiomyopathy
**Semantic type:** Disease or Syndrome
**Definition:** A spontaneous, age-related cardiac disease of rats and mice, characterized by myocardial changes presenting a continuum that begins as focal to multifocal individual cardiomyocyte necrosis attended by a few inflammatory cells progressing at different rates in different animals to include multifocal mononuclear cell inflammation and even fibrosis for larger lesions. (INHAND)
**Synonyms:** - RODENT PROGRESSIVE CARDIOMYOPATHY
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