Isobaric Label Quantification

**Semantic type:** Conceptual Entity

**Definition:** A proteomic quantitation method where isobaric mass tags are added into a sample that is subjected to quantification analysis using liquid chromatography/tandem mass spectrometry (LC-MS/MS). The tagged peptides co-elute with the unlabeled analog peptide in the sample and the amount of total target peptide is determined by comparing the intensities of the reporter ions in the MS/MS spectra.

**Synonyms:** - Isobaric Label Quantitation