Cholic-2,2,4,4-D4 Acid

**Semantic type:** Pharmacologic Substance

**Definition:** A deuterated form of cholic acid with potential diagnostic applications. Upon intravenous administration, cholic-2,2,4,4-D4 acid levels may be used to measure first pass hepatic extraction of cholate, which is influenced primarily by portal blood flow and portal-systemic shunt.

**Synonyms:** - 2,2,4,4-2H Cholate