Ibrexafungerp

**Semantic type:** Pharmacologic Substance

**Definition:** An intravenous and orally bioavailable semisynthetic derivative of enfumafungin with potential antifungal activity. Upon administration, ibrexafungerp inhibits beta-1,3-D-glucan synthase, an enzyme essential for fungal cell wall synthesis. This results in weakening of the fungal cell wall, thereby leading to osmotic lysis and eventually fungal cell death.

**Synonyms:** - IBREXAFUNGERP - IBX - MK 3118 - MK-3118 - MK3118 - SCY 078 - SCY-078 - SCY078