World Of Taxonomy
C162390Level 5

KLF2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KLF2 wild-type allele is located in the vicinity of 19p13.11 and is approximately 3 kb in length. This allele, which encodes krueppel-like factor 2 protein, plays a role in endothelial cell proliferation and T-cell quiescence. A fusion involving this gene and the DDX5 gene may be associated with childhood B acute lymphoblastic leukemia (B-ALL).

**Synonyms:** - Kruppel Like Factor 2 wt Allele - Kruppel-Like Factor 2 (Lung) Gene - LKLF - Lung Kruppel-Like Factor Gene

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