CREM wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CREM wild-type allele is located in the vicinity of 10p11.21 and is approximately 86 kb in length. This allele, which encodes cAMP-responsive element modulator protein, is involved in the modulation of gene transcription. A fusion involving this gene and either the EWSR1 gene or the FUS gene may be associated with epithelial tumors.

**Synonyms:** - CREM-2 - ICER - cAMP Responsive Element Modulator wt Allele - hCREM-2