Trastuzumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. (NCI04)

**Synonyms:** - ABP 980 - ALT02 - Biceltis - CANMab - CT-P06 - CT-P6 - HLX 02 - HLX-02 - HLX02 - Herceptin - Herceptin - Herceptin Biosimilar PF-05280014 - Herceptin Trastuzumab Biosimilar PF-05280014 - Hercessi - Herclon - Hertraz - Herwenda - Herzuma - Immunoglobulin G 1 (Human-Mouse Monoclonal RhuMab HER2gamma1-Chain Antihuman p185(Sup c-erbB2) Receptor), Disulfide with Human-Mouse Monoclonal RhuMab HER2 Light Chain, Dimer - Kanjinti - Ogivri - Ontruzant - PF 05280014 - PF-05280014 - PF05280014 - QL 1701 - QL-1701 - QL1701 - RO0452317 - SB3 - TRASTUZUMAB - Trastuzumab Biosimilar ABP 980 - Trastuzumab Biosimilar ALT02 - Trastuzumab Biosimilar CT-P6 - Trastuzumab Biosimilar HLX02 - Trastuzumab Biosimilar PF-05280014 - Trastuzumab Biosimilar QL1701 - Trastuzumab Biosimilar SB3 - Trastuzumab Biosimilar SIBP-01 - Trastuzumab-anns - Trastuzumab-anns - Trastuzumab-dkst - Trastuzumab-dkst - Trastuzumab-dttb - Trastuzumab-dttb - Trastuzumab-herw - Trastuzumab-pkrb - Trastuzumab-pkrb - Trastuzumab-qyyp - Trastuzumab-qyyp - Trastuzumab-strf - Trastuzumab-strf - Trastuzumab-zerc - Trazimera - Zercepac - rhuMAb HER2 - trastuzumab - trastuzumab biosimilar EG12014