DNA Nucleotidylexotransferase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** DNA nucleotidylexotransferase (509 aa, ~59 kDa) is encoded by the human DNTT gene. This protein plays a role in DNA polymerization and specifically catalyzes the insertion of nucleotides (N regions) at the V(H)-D and D-J(H) junctions of immunoglobulin genes.

**Synonyms:** - DNTT - Deoxynucleotidyl Terminal Transferase - EC 2.7.7.31 - TDT - TdT - Terminal Addition Enzyme - Terminal Deoxynucleotidyltransferase - Terminal Deoxyribonucleotidyl Transferase - Terminal Transferase