DNA Topoisomerase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** DNA topoisomerase 1 (765 aa, ~91 kDa) is encoded by the human TOP1 gene. This protein plays a role in the regulation of DNA topology.

**Synonyms:** - DNA Topoisomerase I - DNA Topoisomerase I - EC 5.99.1.2 - SCL-70 - Scl-70 Antigen - Scl-70 Antigen - Scleroderma-70 - TOP1 - Top1 - Topo I - Topoisomerase (DNA) I - Topoisomerase 1 - Topoisomerase I - Topoisomerase I - Topoisomerase, DNA, I - Type I DNA Topoisomerase