Rilematovir

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** An orally available inhibitor of human respiratory syncytial virus (RSV) fusion protein (F protein), with potential antiviral activity. Upon oral administration, rilematovir specifically targets and binds to F protein on the viral surface, which inhibits RSV F protein-mediated fusion with the host cell membrane and prevents viral entry. This blocks RSV replication, reduces viral load, and decreases the severity of the disease. RSV F protein, a viral surface glycoprotein, plays a key role in RSV fusion with and entry into target cells.

**Synonyms:** - JNJ 53718678 - JNJ-53718678 - JNJ-678 - JNJ-8678 - JNJ53718678 - RILEMATOVIR - RSV F Protein Inhibitor JNJ-53718678 - RSV Fusion Protein Inhibitor JNJ-53718678 - Respiratory Syncytial Virus Fusion Protein Inhibitor JNJ-53718678