Neoantigen-based Therapeutic Cancer Vaccine GRT-R904

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A cancer boosting vaccine consisting of tumor-specific shared neoantigens, which are immunogenic and unique across a subset of patients, with potential immunostimulating and antineoplastic activities. Upon administration of the neoantigen-based therapeutic cancer vaccine GRT-R904, which is administered after the initial administration of the priming vaccine GRT-C903, the peptides stimulate the host immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against the shared neoantigens expressed on tumor cells, which results in tumor cell lysis.

**Synonyms:** - Boosting Cancer Vaccine GRT-R904 - Boosting Vaccine GRT-R904 - GRT R904 - GRT-R904 - GRTR904 - Shared Neoantigen Boosting Cancer Vaccine GRT-R904 - Shared Neoantigen Cancer Vaccine Boost GRT-R904