BAP1-Inactivated Melanocytoma

**Semantic type:** Neoplastic Process

**Definition:** A cutaneous melanocytoma caused by the inactivation of BAP1 tumor suppressor gene. It is characterized by the presence of a predominantly intradermal proliferation of large epithelioid melanocytes with a large amount of eosinophilic cytoplasm, and vesicular nuclei with prominent nucleoli. Progression to melanoma is infrequent.

**Synonyms:** - BAP1-Deficient Tumor - BAP1-Inactivated Cutaneous Melanocytic Neoplasm - BAP1-Inactivated Cutaneous Melanocytic Tumor - BAP1-Inactivated Cutaneous Melanocytoma - BAP1-Inactivated Melanocytic Neoplasm - BAP1-Inactivated Melanocytic Tumor - BAP1-Inactivated Nevus - BAP1-Inactivated Skin Melanocytic Neoplasm - BAP1-Inactivated Skin Melanocytic Tumor - BAP1-Inactivated Spitzoid Nevus - BAPoma - BIM - BIMT - MBAIT - Melanocytic BAP1-Mutated Atypical Intradermal Tumor - Skin BAP1-Inactivated Melanocytoma - Wiesner Nevus