Platform Protocol

**Semantic type:** Intellectual Product

**Definition:** A type of master protocol that tests multiple, targeted therapies for a single disease simultaneously. NOTE: Platform protocols often include an adaptive design that may eliminate or add treatments based on interim analysis. (Saville BR, Berry SM. Efficiencies of platform clinical trials: A vision of the future. Clin Trials. 2016 Jun;13(3):358-66 and Woodcock J, LaVange LM. Master Protocols to Study Multiple Therapies, Multiple Diseases, or Both. N Engl J Med. 2017 Jul 6;377(1):62-70.)