Recombinant Interferon-alpha Inducible Protein 10

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant agent, chemically identical or similar to the endogenous small inducible cytokine B10 (IP-10). Interferon-alpha inducible protein 10 is secreted from macrophages, endothelial cells, and keratinocytes in response to stimulation of IFN-gamma. This agent is a potent inhibitor of angiogenesis, bone marrow colony formation, and is a chemoattractant for monocytes and T-cells, promotes T-cell adhesion to endothelial cells, and probably participates in chronic cell-mediated inflammatory reactions.

**Synonyms:** - CXCL10 - IP 10 - Interferon-gamma Inducible Protein 10