Glutathione S-Transferase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** A class of enzymes that catalyze the reaction of glutathione with an acceptor molecule (an arene oxide) to form an S-substituted glutathione; a key step in detoxification of many substances; start of the mercapturic acid pathway.

**Synonyms:** - EC 2.5.1.18 - GST - Glutathione S-Alkyltransferase - Glutathione S-Aralkyltransferase - Glutathione S-Aryltransferase - S-(Hydroxyalkyl)Glutathione Lyase - glutathione S-transferase