Esuberaprost Sodium

**Semantic type:** Pharmacologic Substance

**Definition:** The sodium salt form of esuberaprost, the 314-d isomer of beraprost, with potential anti-inflammatory activity. Upon administration, esuberaprost activates the prostaglandin E2 receptor EP4 subtype (PTGER4; EP4), and inhibits the nuclear factor-kappa B (NF-kB) pro-inflammatory pathway. This may attenuate cytokine production and decrease inflammation.

**Synonyms:** - Beraprost-314d - CTO 1681 - CTO-1681 - CTO1681 - ESUBERAPROST SODIUM - GP 1681 - GP-1681 - GP1681