Ibandronate Sodium

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.

**Synonyms:** - Bondronate - Boniva - IBANDRONATE SODIUM - ibandronate