STAT5 Protein Family

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Two highly conserved members of the signal transducer and activator of transcription (STAT) protein family, STAT5A and STAT5B. Constitutive phosphorylation of STAT5 proteins, which leads to constitutive activation and aberrant expression of STAT5-dependent genes, has been observed in various neoplastic diseases.

**Synonyms:** - STAT5 - STAT5 Protein - Signal Transducer and Activator of Transcription 5 - Signal Transducer and Activator of Transcription 5 Protein