Immunoglobulin Heavy Chain

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor

**Definition:** A protein complex that consists of two heavy chains (gamma, alpha, delta, epsilon or mu). The larger of the two immunoglobulin chain types determines the immunoglobulin class (G, A, D, E or M, respectively). The heavy chain molecules exhibit the same structure and composition, which consists of constant, variable, and hypervariable regions.

**Synonyms:** - IGH