Recombinant Interleukin-17

**Semantic type:** Amino Acid, Peptide, or Protein|Pharmacologic Substance

**Definition:** A recombinant agent, which is chemically identical or similar to the endogenous cytokine interleukin-17 (IL-17). IL-17 is produced by cytotoxic T cells and stimulates stromal cells to produce pro-inflammatory and hematopoietic cytokines. This cytokine enhances expression of IL-6, IL-8, and ICAM-1 in fibroblasts and appears to induce osteoclastogenesis.

**Synonyms:** - CTLA-8 (Therapeutic) - IL-17 - Interleukin-17