Deleterious POLE Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the POLE gene that is associated with increased risk of disease.

**Synonyms:** - Deleterious DNA Polymerase Epsilon Catalytic Subunit A Gene Mutation - Deleterious DNA Polymerase Epsilon, Catalytic Subunit Gene Mutation - Deleterious POLE Mutation - Deleterious POLE1 Gene Mutation