INPPL1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human INPPL1 wild-type allele is located in the vicinity of 11q13.4 and is approximately 15 kb in length. This allele, which encodes phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 protein, is involved in the regulation of PI3K-dependent insulin signaling. Mutations in the gene are associated with opsismodysplasia.

**Synonyms:** - Inositol Polyphosphate Phosphatase Like 1 wt Allele - Inositol Polyphosphate Phosphatase-Like 1 Gene - OPSMD - SHIP2