Fibrosis 4 Formula

**Semantic type:** Quantitative Concept

**Definition:** A formula that estimates liver pathology through the assessment of a three-parameter blood test, taking into account subject age. FIB-4 = age ([yr] x AST [U/L]) / ((PLT [10(9)/L]) x (ALT [U/L])(1/2)). (Sterling RK, Lissen E, Clumeck N, et. al. Development of a simple noninvasive index to predict significant fibrosis patients with HIV/HCV co-infection. Hepatology 2006;43:1317-1325.)

**Synonyms:** - FIB-4 Formula - FIB-4 Formula - FIBROSIS 4 FORMULA