RAS Family Oncogene

**Semantic type:** Gene or Genome

**Definition:** A family of oncogenes that are highly homologous with the retrovirus-associated DNA sequences (ras) originally isolated from Harvey and Kirsten murine sarcoma viruses. Mutated or overexpressed forms of the human ras genes are associated with constitutive ras GTPase activity, increased cellular proliferation, and cell transformation.

**Synonyms:** - Oncogene RAS - RAS - RAS Oncogene - Retrovirus Associated Sequence Oncogene