RUBCN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RUBCN wild-type allele is located in the vicinity of 3q29 and is approximately 81 kb in length. This allele, which encodes Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, is involved in the modulation of endosome and autophagosome maturation. Mutation of the gene is associated with autosomal recessive spinocerebellar ataxia 15.

**Synonyms:** - KIAA0226 - RDTX - RUBICON - RUNDATAXIN - Rubicon Autophagy Regulator wt Allele - SCAR15