Run Domain Beclin-1-Interacting and Cysteine-Rich Domain-Containing Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (972 aa, ~109 kDa) is encoded by the human RUBCN gene. This protein plays a role in the negative regulation of phosphatidylinositol 3-kinase complex II activity, endocytosis and autophagy.

**Synonyms:** - Baron - Beclin-1 Associated RUN Domain Containing Protein - RUBCN - RUN Domain and Cysteine-Rich Domain Containing, Beclin 1-Interacting Protein - RUN Domain- and Cysteine-Rich Domain-Containing, Beclin-1-Interacting Protein - RUN and Cysteine Rich Domain Containing Beclin 1 Interacting Protein - Rubicon - Rundataxin