Radix Polygalae Extract PDC-1421

**Semantic type:** Pharmacologic Substance

**Definition:** A botanical formulation containing the extract of Radix polygalae, the dry root of Polygala tenuifolia Willd, with potential anti-depressant and sedative activities. Upon oral administration, PDC-1421 inhibits the norepinephrine (NE) plasma membrane transport protein (NET). This inhibits NE reuptake and increases the concentration of NE available for adrenergic neurotransmission.

**Synonyms:** - BLI-1005 - PDC 1421 - PDC-1421 - PDC1421 - POLYGALA TENUIFOLIA ROOT