UGT1A1*6 Allele

**Semantic type:** Gene or Genome

**Definition:** Human UGT1A1*6 allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP-glucuronosyltransferase 1-1*6 protein, plays a role in the transformation of small lipophilic molecules into water-soluble metabolites. Homozygous expression of the UGT1A1*6 allele is associated with decreased enzymatic activity and Gilbert syndrome, neonatal hyperbilirubinemia and intermittent unconjugated hyperbilirubinemia.

**Synonyms:** - NM_000463.3:c.211G>A - UDP Glucuronosyltransferase Family 1 Member A1 c.211G>A - UDP Glucuronosyltransferase Family 1 Member A1*6 Allele - UDP Glycosyltransferase 1 Family, Polypeptide A1 c.211G>A - UDP Glycosyltransferase 1 Family, Polypeptide A1*6 Allele - UGT1A1 NM_000463.3:c.211G>A - UGT1A1 c.211G>A - UGT1A1*6