UGT1A1*60 Allele

**Semantic type:** Gene or Genome

**Definition:** Human UGT1A1*60 allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP-glucuronosyltransferase 1-1 protein, plays a role in the catabolism of small lipophilic molecules. Homozygous expression of the UGT1A1*60 allele is associated with Crigler-Najjar syndrome type II and heterozygous expression is associated with Gilbert syndrome.

**Synonyms:** - UDP Glucuronosyltransferase Family 1 Member A1 c.-3279T>G - UDP Glucuronosyltransferase Family 1 Member A1*60 Allele - UDP Glycosyltransferase 1 Family, Polypeptide A1 c.-3279T>G - UDP Glycosyltransferase 1 Family, Polypeptide A1*60 Allele - UGT1A1 c.-3279T>G - UGT1A1*60