NCCN ALL Response Criteria for Lymphomatous Extramedullary Disease Progressive Disease

**Semantic type:** Intellectual Product

**Definition:** Greater than 25 percent increase in the SPD of patients with mediastinal enlargement. For patients with previous positive PET scan, post-treatment PET must be positive in at least one previously involved site. (Adapted from NCCN Guidelines, Version 1.2020, February 20, 2020)