Activating GNA11 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of the GNA11 gene that results in constitutive activation of both guanine nucleotide-binding protein subunit alpha-11 and its downstream signaling pathways.

**Synonyms:** - Activating G Protein Subunit Alpha 11 Gene Mutation - Activating GA11 Gene Mutation - Activating GNA-11 Gene Mutation - Activating GNA11 Mutation - Activating Guanine Nucleotide Binding Protein (G Protein), Alpha 11 Gene Mutation - Activating Guanine Nucleotide-Binding Protein, Alpha-11 Gene Mutation - GNA11 Activating Gene Mutation - GNA11 Activating Mutation