Molnupiravir

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable prodrug of EIDD-1931, the synthetic ribonucleoside derivative N4-hydroxycytidine and ribonucleoside analog, with potential antiviral activity against a variety of RNA viruses. Upon oral administration, molnupiravir, being a prodrug, is metabolized into its active form EIDD-1931 and converted into its triphosphate (TP) form. The TP form of EIDD-1931 is incorporated into RNA and inhibits the action of viral RNA-dependent RNA polymerase. This results in the termination of RNA transcription and decreases viral RNA production, and viral RNA replication.

**Synonyms:** - EIDD 2801 - EIDD-2801 - EIDD2801 - Lagevrio - MK 4482 - MK-4482 - MK4482 - MOLNUPIRAVIR - N4-Hydroxycytidine, 5'-Isopropyl Ester - SARS-CoV-2 antiviral agents: molnupiravir - Uridine, 4-Oxime, 5'-(2-Methylpropanoate)