Saponin-based Adjuvant

**Semantic type:** Pharmacologic Substance

**Definition:** An adjuvant composed of Quillaja saponins, cholesterol and phospholipid, with potential immunoadjuvant activity. Upon administration with a vaccine, the saponin-based adjuvant may increase both cell-mediated and antibody mediated immune responses against the vaccine's targeted antigen(s). It may also reduce the amount of antigen(s) needed in the vaccine to induce an efficient immune response in the host.

**Synonyms:** - MATRIX-M1 ADJUVANT - Matrix-M