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C172754Level 8

SARS-CoV-2 Lentiviral-based Dendritic Cell Vaccine LV-SMENP-DC

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A vaccine consisting of dendritic cells (DCs) that are modified with lentivirus vectors expressing engineered SARS-CoV-2 minigenes SMENP and immune modulatory genes, with potential immunizing activity against SARS-CoV-2. Upon administration, SARS-CoV-2 lentiviral-based DC vaccine LV-SMENP-DC may elicit a specific cytotoxic T-cell (CTL) response against the SARS-CoV-2 viral antigens encoded by the minigenes.

**Synonyms:** - LV-SMENP-DC - LV-SMENP-DC Vaccine - SARS-CoV-2 Lentiviral-based DC Vaccine LV-SMENP-DC

GET/api/v1/systems/nci_thesaurus/nodes/C172754
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