Human Papillomavirus-Related Sinonasal Multiphenotypic Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** A distinctive HPV-related non-keratinizing squamous cell carcinoma of the sinonasal tract arising most frequently from the maxillary sinus or nasal cavity. Most patients present with nasal obstruction and/or epistaxis. It is characterized by the presence of basaloid cell proliferations separated by collagenous fibrous bands. The basaloid cells align around microcystic spaces.

**Synonyms:** - HPV-Associated Multiphenotypic Sinonasal Carcinoma - HPV-Associated Sinonasal Multiphenotypic Carcinoma - HPV-Related Multiphenotypic Sinonasal Carcinoma - HPV-Related Sinonasal Multiphenotypic Carcinoma - Human Papillomavirus-Associated Multiphenotypic Sinonasal Carcinoma - Human Papillomavirus-Associated Sinonasal Multiphenotypic Carcinoma - Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma - Sinonasal HPV-Associated Multiphenotypic Carcinoma - Sinonasal HPV-Related Carcinoma with Adenoid Cystic-Like Features - Sinonasal HPV-Related Multiphenotypic Carcinoma - Sinonasal Human Papillomavirus-Associated Multiphenotypic Carcinoma - Sinonasal Human Papillomavirus-Related Carcinoma with Adenoid Cystic-Like Features - Sinonasal Human Papillomavirus-Related Carcinoma with Adenoid Cystic-Like Features - Sinonasal Human Papillomavirus-Related Multiphenotypic Carcinoma