Gridegalutamide

**Semantic type:** Pharmacologic Substance

**Definition:** An orally bioavailable androgen receptor (AR) degrader, with potential antineoplastic activity. Upon administration, gridegalutamide causes degradation of AR, prevents AR-mediated signaling and inhibits the proliferation of AR-overexpressing tumor cells. AR plays a key role in tumor cell proliferation in castration-resistant prostate cancer (CRPC).

**Synonyms:** - BMS 986409 - BMS-986409 - BMS986409 - CC 1083611 - CC-1083611 - CC1083611 - CEL 010355 - CEL-010355 - CEL010355 - GRIDEGALUTAMIDE