Frameshift Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A mutation occurring within the protein-coding region of a gene which results in a shift in the reading frame of the encoded protein. Frameshift mutations often result in the premature truncation of a gene product.

**Synonyms:** - Frameshift - Frameshift Mutation Abnormality - Frameshift Variant - Mutation, Frameshift - Reading Frame Shift Mutation - frameshift mutation - fs