Hsp90 Inhibitor TQB3474

**Semantic type:** Pharmacologic Substance

**Definition:** An inhibitor of heat shock protein 90 (Hsp90), with potential antineoplastic activity. Upon administration, Hsp90 inhibitor TQB3474 specifically blocks Hsp90, which inhibits its chaperone function and promotes the proteasomal degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. This may lead to an inhibition of tumor cell proliferation. Hsp90, a chaperone complex protein upregulated in a variety of tumor cell types, regulates the folding and degradation of many oncogenic signaling proteins.

**Synonyms:** - Heat Shock Protein 90 Inhibitor TQB3474 - TQB 3474 - TQB-3474 - TQB3474