MVA-BN Smallpox Vaccine

**Semantic type:** Immunologic Factor|Pharmacologic Substance

**Definition:** A vaccine consisting of modified vaccinia Ankara-Bavarian Nordic (MVA-BN), a live, attenuated, non-replicating, proprietary version of the MVA virus, used for the prevention of smallpox and monkeypox, with potential antineoplastic activity. Upon intratumoral administration, MVA-BN smallpox vaccine may induce both cellular and humoral immune responses, which may lead to tumor cell lysis.

**Synonyms:** - Imvamune - Imvanex - JYNNEOS - MVA Smallpox Vaccine - Modified Vaccinia Ankara - Bavarian Nordic Smallpox Vaccine - Modified Vaccinia Ankara Smallpox Vaccine - VACCINIA VIRUS MODIFIED STRAIN ANKARA-BAVARIAN NORDIC NON-REPLICATING ANTIGEN